Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092146 | 1.00 | PPARG (0.48) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL29451165 | 0.90 | PPARG (0.45) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092143 | 0.87 | NPC1 (0.51) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092142 | 0.87 | NPC1 (0.51) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092156 | 0.86 | MAOB (0.59) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL22092152 | 0.86 | PPARG (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092178 | 0.86 | MAOB (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092151 | 0.86 | PPARG (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092176 | 0.86 | MAOB (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22092155 | 0.86 | MAOB (0.59) | PPARGPPARACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020122380-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CIRCADIAN RHYTHM-RELATED DISORDERS, COMPRISING OXYIMINOMETHYLBENZENE DERIVATIVE AS ACTIVE INGREDIENT | 고려대학교 산학협력단 | 2020-06-18 | — | — | WO | claimed |
| WO-2020122380-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CIRCADIAN RHYTHM-RELATED DISORDERS, COMPRISING OXYIMINOMETHYLBENZENE DERIVATIVE AS ACTIVE INGREDIENT | 고려대학교 산학협력단 | 2020-06-18 | — | — | WO | disclosed |