Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | AURKA | O14965 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22095223 | 0.93 | AURKA (0.77) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095570 | 0.91 | MEN1 (0.82) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL23928595 | 0.89 | MEN1 (0.73) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095538 | 0.89 | KDM4E (0.78) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22094961 | 0.89 | AURKA (0.79) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095056 | 0.88 | AURKA (0.80) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22094958 | 0.88 | MEN1 (0.71) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095589 | 0.88 | MEN1 (0.68) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095643 | 0.87 | MEN1 (0.70) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL22095167 | 0.87 | MEN1 (0.72) | MEN1KMT2AAURKATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123855-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2020-06-18 | — | — | WO | disclosed |