Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22096041 | 0.85 | STAT5B (0.56) | STAT5BALDH1A1TP53CYP1A2CYP2C19 | |
| SCHEMBL22096017 | 0.85 | STAT5B (0.65) | STAT5BPOLBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22096040 | 0.82 | STAT5B (0.55) | STAT5BPOLBCYP1A2CYP2C19 | |
| SCHEMBL22096042 | 0.81 | STAT5B (0.54) | STAT5BPOLBPOLQ | |
| SCHEMBL22096019 | 0.77 | STAT5B (0.62) | STAT5BHSP90AA1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22096016 | 0.74 | STAT5B (0.81) | STAT5BPOLBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22096024 | 0.74 | STAT5B (0.79) | STAT5BPOLBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22096023 | 0.73 | STAT5B (0.65) | STAT5BPOLB | |
| SCHEMBL22096022 | 0.73 | STAT5B (0.81) | STAT5BPOLBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22096043 | 0.72 | STAT5B (0.68) | STAT5BPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683286-B2 | Furazan-3-carboxylic acid derivatives and use thereof in treatment of cancer | FREIE UNIVERSITAET BERLIN (DE) | 2020-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683286-B2 | Furazan-3-carboxylic acid derivatives and use thereof in treatment of cancer | FLT3, MCL1, MYD88 | STAT5B 59/4885POLB 4594/4885HSP90AA1 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.