Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114271 | 0.85 | ANPEP (0.47) | ANPEPCA1CA2ZDHHC7TSHR | |
| SCHEMBL28113852 | 0.85 | ANPEP (0.47) | ANPEPCA1CA2ZDHHC7TSHR | |
| SCHEMBL23102141 | 0.84 | SMN1; SMN2 (0.42) | CA1CA2ZDHHC7SMN1; SMN2HSD17B10 | |
| SCHEMBL21359152 | 0.84 | SMN1; SMN2 (0.42) | CA1CA2ZDHHC7SMN1; SMN2HSD17B10 | |
| SCHEMBL10836597 | 0.83 | ANPEP (0.42) | ANPEPCA1CA2ZDHHC7SMN1; SMN2 | |
| SCHEMBL7427794 | 0.83 | KDM4E (0.40) | CA1CA2ZDHHC7SMN1; SMN2CHRNB2 | |
| SCHEMBL23418589 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14SCN1ASCN2ASCN3A | |
| SCHEMBL3668467 | 0.82 | ANPEP (0.36) | ANPEPCA1CA2ZDHHC7SMN1; SMN2 | |
| SCHEMBL11387958 | 0.80 | CA14 (0.42) | ANPEPCA1CA2SMN1; SMN2PAOX | |
| SCHEMBL11372807 | 0.79 | PAOX (0.42) | ANPEPCA1CA2SMN1; SMN2PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331884-B1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | KYORIN SEIYAKU KK (JP) | 2020-06-17 | — | — | EP | disclosed |