Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 18/20 | 0.60 |
| ▸ | JAK3 | P52333 | 18/20 | 0.60 |
| ▸ | JAK1 | P23458 | 15/20 | 0.60 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941749 | 0.91 | JAK3 (0.65) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22089802 | 0.91 | JAK3 (0.65) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL29942192 | 0.90 | JAK2 (0.65) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22089909 | 0.90 | JAK2 (0.65) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL29941801 | 0.88 | JAK2 (0.46) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22089912 | 0.88 | JAK2 (0.46) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL24852601 | 0.87 | JAK2 (0.62) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22097936 | 0.87 | JAK2 (0.62) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL27448371 | 0.87 | JAK2 (0.62) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL22097994 | 0.86 | JAK2 (0.64) | JAK2JAK3JAK1TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119819-A1 | BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |