Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541789 | 0.83 | HTR2A (0.49) | FFAR1CYP4F2CYP4A11ALDH1A1GPR88 | |
| SCHEMBL24845309 | 0.83 | FFAR1 (0.50) | FFAR1GLAFFAR4MEN1KMT2A | |
| SCHEMBL11902326 | 0.83 | HTR2A (0.49) | FFAR1CYP4F2CYP4A11ALDH1A1GPR88 | |
| SCHEMBL11902614 | 0.83 | HTR2A (0.49) | FFAR1CYP4F2CYP4A11ALDH1A1GPR88 | |
| SCHEMBL15428485 | 0.83 | CYP1A2 (0.37) | GLAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL26186801 | 0.83 | FFAR1 (0.45) | FFAR1GLAFFAR4ADORA2AGRM2 | |
| SCHEMBL26186935 | 0.83 | FFAR1 (0.45) | FFAR1GLAFFAR4ADORA2AGRM2 | |
| SCHEMBL30637003 | 0.83 | FFAR1 (0.45) | FFAR1GLAFFAR4ADORA2AGRM2 | |
| SCHEMBL17385720 | 0.82 | CYP4F2 (0.44) | FFAR1CYP4F2CYP4A11GRM2GRM3 | |
| SCHEMBL26186746 | 0.81 | HTR2A (0.51) | FFAR1GLAFFAR4KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |