Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148800 | 0.90 | HDAC1 (0.55) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL16147569 | 0.86 | ROCK1 (0.46) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL16147383 | 0.86 | HDAC1 (0.47) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL16148197 | 0.85 | HDAC1 (0.47) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL17671662 | 0.83 | HDAC1 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL17672181 | 0.83 | HDAC1 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL17671849 | 0.81 | HDAC1 (0.52) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL17672110 | 0.81 | HDAC1 (0.52) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL16147566 | 0.81 | HDAC1 (0.45) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL16147982 | 0.81 | HDAC1 (0.46) | HDAC1HDAC2HDAC6HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420934-B2 | PPAR agonists | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2022-08-23 | — | — | US | disclosed |
| US-20200190019-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420934-B2 | PPAR agonists | PPARG, PPARD, PPARA | OXTR 4381/4885AVPR1A 3463/4885HDAC1 1137/4885 |
| US-20200190019-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | OXTR 4381/4885AVPR1A 3463/4885HDAC1 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.