Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.70 |
| ▸ | GABRP | O00591 | 1/20 | 0.70 |
| ▸ | GABRD | O14764 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | KLK3 | P07288 | 1/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.70 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.70 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.70 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.70 |
| ▸ | GABRE | P78334 | 1/20 | 0.70 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465765 | 0.92 | AR (0.83) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL582006 | 0.85 | AR (0.80) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL23378335 | 0.84 | AR (0.81) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL582695 | 0.84 | AR (0.81) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL7035063 | 0.84 | AR (0.87) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL31071654 | 0.83 | AR (0.71) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL22117698 | 0.83 | AR (0.71) | ARGABRPGABRDNR1I2NR3C1 | |
| SCHEMBL21788386 | 0.82 | AR (0.87) | ARGABRPGABRDNR1I2NR3C1 | |
| Enzalutamide SCHEMBL189749 | 0.82 | AR (1.00) | ARGABRPGABRDNR1I2NR3C1 | |
| Enzalutamide SCHEMBL29352764 | 0.82 | AR (1.00) | ARGABRPGABRDNR1I2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |