SCHEMBL2210133

SCHEMBL2210133

C(=C(c1ccccc1)c1ccccc1)c1ccc(N(c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.57
CYP11B2 P19099 2/20 0.57
ESR1 P03372 2/20 0.53
PTGS2 P35354 4/20 0.53
ESR2 Q92731 1/20 0.48
ALDH1A1 P00352 3/20 0.45
MAPT P10636 3/20 0.45
MAPK1 P28482 1/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP2D6 P10635 1/20 0.44
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128938 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL14018365 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL6140273 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL7570019 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL6032733 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL133557 0.98 CYP19A1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL4310935 0.96 ESR1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL4310932 0.96 ESR1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL14044715 0.96 ESR1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2
SCHEMBL14018371 0.96 ESR1 (0.55) CYP19A1CYP11B2ESR1PTGS2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP claimed
US-8007971-B2 Tris(enylaryl)amine containing photoconductors XEROX CORPORATION (US) 2011-08-30 US claimed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
EP-2141546-A1 Photoconductors containing Tris and Bis(enylaryl)arylamine Xerox Corporation (US) 2010-01-06 EP claimed
US-20090325096-A1 TRIS(ENYLARYL)AMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US disclosed
US-20220197161-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC EQUIPMENT FUJI ELECTRIC CO., LTD. (JP) 2022-06-23 US disclosed
US-11143976-B2 Photoconductor having interlayer for hole injection promotion FUJI ELECTRIC CO., LTD. (JP) 2021-10-12 US disclosed
US-11036151-B2 Electrophotographic photoreceptor, method for manufacturing same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2021-06-15 US disclosed
US-20210124279-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING THE PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2021-04-29 US disclosed
US-10962893-B2 Photosensitive body for electrophotography, method for producing same and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2021-03-30 US disclosed
EP-3415989-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2020-07-22 EP disclosed
US-6391482-B1 4,4,8,8-TETRAKIS(1H-PYRAZOL-1-YL)PYRAZABOLE; HIGH SPEED RESPONSE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-05-21 US disclosed
EP-0812820-B1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM TAKASAGO PERFUMERY CO LTD (JP) 2001-01-17 EP disclosed
US-6172264-B1 REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-09 US disclosed
EP-1026222-A2 Organic material for electroluminescent device and electroluminescent device using the same Matsushita Electric Industrial Co., Ltd. (JP) 2000-08-09 EP disclosed
US-5989765-A CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-11-23 US disclosed
US-5910610-A Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-06-08 US disclosed
EP-0812820-A1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM Takasago International Corporation (JP) 1997-12-17 EP disclosed