SCHEMBL2210176

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2210697	0.92	PIK3CA (0.36)	YES1METCYP3A4ACP1MEN1
	SCHEMBL3704091	0.91	YES1 (0.48)	YES1METCYP3A4FGFR2PRKACG
	SCHEMBL3698189	0.84	YES1 (0.46)	YES1METCYP3A4FGFR2PRKACG
	SCHEMBL3707719	0.83	YES1 (0.47)	YES1METCYP3A4FGFR2PRKACG
	SCHEMBL3694325	0.83	FGFR2 (0.40)	YES1METCYP3A4ACP1FGFR2
	SCHEMBL3698351	0.82	PIK3CA (0.41)	YES1METACP1FGFR2ABL1
	SCHEMBL2206270	0.82	MAPT (0.46)	ACP1MEN1USP2KMT2AKDR
	SCHEMBL2209662	0.81	YES1 (0.44)	YES1METCYP3A4MEN1KMT2A
	SCHEMBL3701368	0.79	YES1 (0.50)	YES1METCYP3A4FGFR2ABL1
	SCHEMBL2206413	0.77	FGFR2 (0.39)	YES1METCYP3A4FGFR2AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.