Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | BAD | Q92934 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284960 | 0.79 | BCL2L1 (0.58) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL3797823 | 0.77 | BCL2L1 (0.56) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL18973499 | 0.76 | CES1 (0.41) | BCL2L1BADNOS3NOS1NOS2 | |
| SCHEMBL16239399 | 0.75 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL16646844 | 0.74 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL630475 | 0.74 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL11316442 | 0.74 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL15054072 | 0.74 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL10828971 | 0.74 | BCL2L1 (0.52) | BCL2L1BADGRIA1GRIA2GRIA3 | |
| SCHEMBL1535927 | 0.73 | BCL2L1 (0.50) | BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119592-A1 | NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |