Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212421 | 0.94 | HRH3 (0.47) | HRH3CYP2D6MCHR1 | |
| SCHEMBL2208189 | 0.90 | HRH3 (0.64) | HRH3RBP4MCHR1 | |
| SCHEMBL2208886 | 0.90 | HRH3 (0.61) | HRH3RBP4MCHR1 | |
| SCHEMBL2210901 | 0.88 | HRH3 (0.55) | HRH3RBP4MCHR1 | |
| SCHEMBL2211215 | 0.88 | HRH3 (0.57) | HRH3RBP4MCHR1 | |
| SCHEMBL2211153 | 0.88 | HRH3 (0.65) | HRH3RBP4MCHR1 | |
| SCHEMBL2214281 | 0.87 | HRH3 (0.66) | HRH3MCHR1 | |
| SCHEMBL2213031 | 0.87 | HRH3 (0.53) | HRH3RBP4MCHR1 | |
| SCHEMBL2211838 | 0.87 | HRH3 (0.52) | HRH3MCHR1 | |
| SCHEMBL2213067 | 0.86 | HRH3 (0.52) | HRH3RBP4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | claimed |