Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.58 |
| ▸ | CCR1 | P32246 | 5/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753069 | 0.96 | CCR3 (0.62) | CCR3CCR1MCHR1ALDH1A1KDM4E | |
| SCHEMBL2212794 | 0.91 | CCR3 (0.59) | CCR3CCR1MCHR1ALDH1A1KDM4E | |
| SCHEMBL2213758 | 0.90 | CCR3 (0.63) | CCR3CCR1MCHR1ALDH1A1SIGMAR1 | |
| SCHEMBL2210125 | 0.89 | CCR3 (0.67) | CCR3CCR1MCHR1SIGMAR1MEN1 | |
| SCHEMBL2214427 | 0.87 | CCR3 (0.65) | CCR3CCR1MCHR1ALDH1A1KDM4E | |
| SCHEMBL2209757 | 0.86 | CCR3 (0.62) | CCR3CCR1MCHR1ALDH1A1SIGMAR1 | |
| SCHEMBL2214179 | 0.84 | CCR3 (0.64) | CCR3CCR1MCHR1SIGMAR1MEN1 | |
| SCHEMBL2210708 | 0.84 | CCR3 (0.68) | CCR3CCR1MCHR1SIGMAR1MEN1 | |
| SCHEMBL2210858 | 0.84 | CCR3 (0.64) | CCR3CCR1MCHR1SIGMAR1MEN1 | |
| SCHEMBL2212834 | 0.82 | CCR3 (0.62) | CCR3CCR1MCHR1POLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |