Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 6/20 | 0.63 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.63 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561296 | 0.91 | SLCO1B1 (0.60) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL23863821 | 0.91 | SLCO1B1 (0.63) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL19715763 | 0.90 | SLCO1B1 (0.79) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL22108098 | 0.87 | SLCO1B1 (0.71) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL19748975 | 0.86 | SLCO1B1 (0.66) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL30338352 | 0.86 | SLCO1B1 (0.47) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL22108103 | 0.85 | SLCO1B1 (0.66) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL22108255 | 0.85 | SLCO1B1 (0.66) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL22108246 | 0.85 | SLCO1B1 (0.64) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL22108305 | 0.85 | SLCO1B1 (0.67) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666771-A1 | LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-06-17 | — | — | EP | disclosed |