Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | PREP | P48147 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178849 | 1.00 | DPP4 (0.50) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18681280 | 0.84 | DPP4 (0.47) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL13614085 | 0.84 | DPP4 (0.47) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL14985781 | 0.81 | DPP4 (0.54) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL14623965 | 0.81 | DPP4 (0.54) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL19944791 | 0.81 | DPP4 (0.54) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL26788112 | 0.81 | F2 (0.43) | PREPACESMN1; SMN2POLBPDK2 | |
| SCHEMBL26787826 | 0.81 | PREP (0.46) | PREPACEKDM4ESMN1; SMN2 | |
| SCHEMBL852542 | 0.80 | POLB (0.52) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL4437850 | 0.80 | POLB (0.52) | DPP4DPP8PREPFAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157942-B1 | SITE SPECIFIC PROTEIN MODIFICATIONS | NOVARTIS AG (CH) | 2020-06-17 | — | — | EP | disclosed |