SCHEMBL22112573

SCHEMBL22112573

c1ccc(-n2c3ccccc3c3cc(-c4cc(-c5ccc6ccc7cccnc7c6n5)cc5c4c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPY5R Q15761 2/20 0.33
METAP2 P50579 1/20 0.33
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
PTGER4 P35408 1/20 0.32
PTGES O14684 1/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22112836 0.87 KDM4E (0.32) KDM4EATML3MBTL1NPY5RSIRT2
SCHEMBL22112431 0.87 KDM4E (0.32) KDM4EATML3MBTL1NPY5R
SCHEMBL17522009 0.86 KDM4E (0.40) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL17899355 0.86 CCR1 (0.41) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL15930287 0.83 KDM4E (0.41) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL17789515 0.82 KDM4E (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL17789422 0.82 KDM4E (0.36) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL17782978 0.82 KDM4E (0.36) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL19486808 0.82 TOP1 (0.35) KDM4EATML3MBTL1TSHRALDH1A1
SCHEMBL13872009 0.81 KDM4E (0.43) KDM4EATML3MBTL1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 WO disclosed