Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22115377 | 0.92 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL22115375 | 0.81 | CSF1R (0.36) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL22115371 | 0.80 | CSF1R (0.34) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL22115370 | 0.78 | CSF1R (0.47) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL16028907 | 0.77 | CSF1R (0.58) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL22115364 | 0.73 | CSF1R (0.48) | CSF1RPDGFRAPDGFRBMETFLT3 | |
| SCHEMBL23900693 | 0.69 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL22115367 | 0.68 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL16028856 | 0.68 | CSF1R (0.61) | CSF1RPDGFRAPDGFRBMETKDR | |
| SCHEMBL23888680 | 0.66 | CSF1R (0.50) | CSF1RPDGFRAPDGFRBMETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968287-B1 | N-ACYL-N'-(PYRIDIN-2-YL) UREAS AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES | DECIPHERA PHARMACEUTICALS LLC (US) | 2020-06-24 | — | — | EP | claimed |