SCHEMBL22115385

SCHEMBL22115385

N#Cc1c(-c2ccccc2)nc(-c2ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc2)nc1-c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 12/20 0.66
ADORA2A P29274 11/20 0.66
HSD17B10 Q99714 1/20 0.66
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
SQOR Q9Y6N5 1/20 0.56
HPGD P15428 2/20 0.56
ALDH1A1 P00352 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
KDM4E B2RXH2 2/20 0.53
RXFP1 Q9HBX9 1/20 0.53
POLB P06746 1/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20041347 0.91 ADORA1 (0.77) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19885511 0.86 HTT (0.53) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19885521 0.85 HPGD (0.74) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19885514 0.84 HTT (0.54) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19313767 0.83 ADORA1 (0.62) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19313789 0.82 ADORA1 (0.60) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19885518 0.82 ADORA1 (0.76) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19313598 0.81 ADORA1 (0.59) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL19313790 0.81 ADORA1 (0.59) ADORA1ADORA2AHSD17B10MEN1KMT2A
SCHEMBL24322312 0.81 ADORA1 (0.55) ADORA1ADORA2AHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210210694-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2021-07-08 US disclosed
US-10950801-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2021-03-16 US disclosed
EP-3754734-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2020-12-23 EP disclosed
US-20200287142-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM LTD. (KR) 2020-09-10 US disclosed
EP-3667749-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-06-17 EP disclosed