SCHEMBL22119477

SCHEMBL22119477

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1CCCNC(=O)NCc1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28392585 0.94 STING1 (0.82) STING1
SCHEMBL29200620 0.93 STING1 (0.84) STING1
SCHEMBL28392479 0.92 STING1 (0.82) STING1
SCHEMBL22134956 0.91 STING1 (0.84) STING1
SCHEMBL22135208 0.91 STING1 (0.83) STING1
SCHEMBL29200540 0.91 STING1 (1.00) STING1
SCHEMBL22135305 0.91 STING1 (0.84) STING1
SCHEMBL19449091 0.90 STING1 (1.00) STING1
SCHEMBL28394351 0.90 STING1 (0.77) STING1
SCHEMBL28394342 0.90 STING1 (0.77) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658992-A Benzimidazole compound, preparation method and pharmaceutical application thereof 中国医学科学院药物研究所 2024-03-08 CN disclosed
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed
CN-110963997-A Heterocyclic amide compound, pharmaceutical composition containing same, and preparation method and application of heterocyclic amide compound 四川科伦博泰生物医药股份有限公司 2020-04-07 CN disclosed