SCHEMBL2212043

SCHEMBL2212043

COc1nc(C)cs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6181092 0.75
SCHEMBL2628982 0.75
SCHEMBL12724530 0.73
SCHEMBL17680549 0.73
SCHEMBL27549260 0.73
SCHEMBL12778759 0.73 SMN1; SMN2 (0.40)
Bromide SCHEMBL28091559 0.73 POLB (0.45)
SCHEMBL14392983 0.72 POLB (0.44)
SCHEMBL10919613 0.70 GCK (0.48)
SCHEMBL15881332 0.70 POLB (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US claimed
EP-3790876-B1 ENDOPARASITIC DEPSIPEPTIDES ZOETIS SERVICES LLC (US) 2025-04-30 EP disclosed
CN-112384511-B Endoparasite depsipeptides 硕腾服务有限责任公司 2024-01-30 CN disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-20220323540-A1 Endoparasitic Depsipeptides ZOETIS SERVICES LLC 2022-10-13 US disclosed
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed
WO-2021252307-A1 RIPK1 INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME CORP. (US) 2021-12-16 WO disclosed
US-20070155748-A1 N-sulfonyl-alpha-amino-acid derivatives SYNGENTA CROP PROTECTION, INC. 2007-07-05 US disclosed
EP-1741715-A1 Epothilone derivatives and their synthesis and use Novartis AG (CH) 2007-01-10 EP disclosed
EP-1045833-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER INC. (US) 2000-10-25 EP disclosed
WO-1999035130-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER PHARMACEUTICALS INC. (JP) 1999-07-15 WO disclosed
EP-0232623-B1 1-CARBACEPHALOSPORIN ANTIBIOTICS ELI LILLY AND COMPANY (US) 1993-03-17 EP disclosed
US-4892942-A 1-CARBA (DETHIA)CEPHALOSPORINS ELI LILLY AND COMPANY (US) 1990-01-09 US disclosed
US-4791106-A 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1988-12-13 US disclosed
EP-0232623-A1 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1987-08-19 EP disclosed
US-4161571-A GELATION INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-07-17 US disclosed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US disclosed