Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.51 |
| ▸ | JAK1 | P23458 | 19/20 | 0.51 |
| ▸ | TYK2 | P29597 | 19/20 | 0.51 |
| ▸ | JAK3 | P52333 | 19/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436566 | 0.84 | JAK2 (0.62) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19436506 | 0.84 | JAK2 (0.62) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL6023576 | 0.82 | KMT2A (0.56) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19437515 | 0.82 | KMT2A (0.63) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22121361 | 0.81 | KMT2A (0.54) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19437503 | 0.79 | KMT2A (0.74) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19451670 | 0.79 | KMT2A (0.55) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19436552 | 0.78 | PTGER4 (0.56) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL22121416 | 0.78 | KMT2A (0.57) | JAK2JAK1TYK2JAK3KMT2A | |
| Bromide SCHEMBL28608182 | 0.77 | PTGER4 (0.55) | JAK2JAK1TYK2JAK3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |