SCHEMBL22122701

SCHEMBL22122701

[N-]=[N+]=NCc1ccc(NC(=O)CCC(=O)O)cn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A1 P04798 1/20 0.46
▸ POLB P06746 2/20 0.44
▸ BCHE P06276 1/20 0.44
▸ MAPT P10636 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ TSHR P16473 1/20 0.40
▸ GLA P06280 1/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ CASP2 P42575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17060910 0.85 P4HTM (0.37) POLBMAPTKMT2AMEN1SMN1; SMN2
SCHEMBL17060912 0.85 P4HTM (0.37) POLBMAPTKMT2AMEN1SMN1; SMN2
SCHEMBL22122715 0.85 SMN1; SMN2 (0.43) L3MBTL1SMN1; SMN2HDAC3HDAC8NCOR2
SCHEMBL22122705 0.84 SMN1; SMN2 (0.41) MAPTKMT2AMEN1L3MBTL1SMN1; SMN2
SCHEMBL22150193 0.82 GAA (0.39) POLBMAPTKMT2AMEN1L3MBTL1
SCHEMBL28544744 0.80 HDAC8 (0.43) POLBMAPTKMT2AMEN1L3MBTL1
SCHEMBL22149955 0.79 SMN1; SMN2 (0.38) MAPTKMT2AMEN1L3MBTL1SMN1; SMN2
SCHEMBL22150881 0.79 GAA (0.37) POLBMAPTKMT2AMEN1L3MBTL1
SCHEMBL22150196 0.78 HDAC8 (0.39) SMN1; SMN2HDAC3HDAC8NCOR2
SCHEMBL29391711 0.78 CA1 (0.44) POLBMAPTKMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240300896-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2024-09-12 — — US disclosed
US-11999696-B2 Heterocyclic azide units and their use in polymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2024-06-04 — — US disclosed
EP-3898586-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS Illumina Cambridge Limited (GB) 2021-10-27 — — EP disclosed
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-09-16 — — US disclosed
WO-2020126598-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300896-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS POLL, PCNA, DNMT3A CYP1A1 2117/4885POLB 23/4885BCHE 2346/4885
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS POLL, PCNA, DNMT3A CYP1A1 2117/4885POLB 23/4885BCHE 2346/4885
US-11999696-B2 Heterocyclic azide units and their use in polymer coatings POLL, PCNA, DNMT3A CYP1A1 2117/4885POLB 23/4885BCHE 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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