Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209777 | 0.83 | CALCRL (0.41) | CALCRLCYP3A4 | |
| SCHEMBL2209770 | 0.83 | CALCRL (0.41) | CALCRLCYP3A4 | |
| SCHEMBL2213435 | 0.82 | CALCRL (0.40) | CALCRLCYP3A4 | |
| SCHEMBL2213426 | 0.82 | CALCRL (0.40) | CALCRLCYP3A4 | |
| SCHEMBL2211635 | 0.82 | CALCRL (0.51) | CALCRLCYP3A4 | |
| SCHEMBL2209806 | 0.81 | CALCRL (0.50) | CALCRLCYP3A4 | |
| SCHEMBL2212018 | 0.77 | MIF (0.32) | CALCRL | |
| SCHEMBL2212014 | 0.77 | MIF (0.32) | CALCRL | |
| SCHEMBL3879914 | 0.76 | CALCRL (0.40) | CALCRLCYP3A4 | |
| SCHEMBL3879907 | 0.76 | CALCRL (0.40) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013213-B1 | CONSTRAINED COMPOUNDS AS CGRP-RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-07-27 | — | — | EP | disclosed |