Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 17/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.49 |
| ▸ | LCK | P06239 | 7/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22154344 | 0.94 | PTK6 (0.54) | PTK6AURKBLCKMKNK1MKNK2 | |
| SCHEMBL22124009 | 0.93 | PTK6 (0.48) | PTK6AURKBLCK | |
| SCHEMBL30177993 | 0.93 | PTK6 (0.48) | PTK6AURKBLCK | |
| SCHEMBL22124899 | 0.91 | PTK6 (0.56) | PTK6AURKBLCKMKNK1MKNK2 | |
| SCHEMBL30177799 | 0.91 | PTK6 (0.56) | PTK6AURKBLCKMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL25173591 | 0.91 | PTK6 (0.55) | PTK6AURKBLCKMKNK1MKNK2 | |
| SCHEMBL30183124 | 0.90 | PTK6 (0.46) | PTK6AURKBLCKMAPKAPK5 | |
| SCHEMBL22142955 | 0.89 | PTK6 (0.44) | PTK6AURKBLCKMAPKAPK5 | |
| SCHEMBL22139096 | 0.89 | PTK6 (0.44) | PTK6AURKBLCKMAPKAPK5 | |
| SCHEMBL22142746 | 0.89 | PTK6 (0.47) | PTK6AURKBLCKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | claimed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | claimed |
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |