Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 6/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125006 | 0.94 | PTK6 (0.48) | TTKPTK6LCKAURKB | |
| SCHEMBL22123995 | 0.93 | PTK6 (0.48) | TTKPTK6LCKAURKB | |
| SCHEMBL22124377 | 0.92 | TTK (0.46) | TTKPTK6LCKAURKB | |
| SCHEMBL24112317 | 0.92 | PTK6 (0.47) | TTKPTK6LCKAURKB | |
| SCHEMBL25436549 | 0.92 | PTK6 (0.47) | TTKPTK6LCKAURKB | |
| SCHEMBL22124987 | 0.92 | PTK6 (0.48) | TTKPTK6LCKAURKB | |
| SCHEMBL28919797 | 0.91 | PTK6 (0.50) | TTKPTK6LCKAURKB | |
| SCHEMBL22124372 | 0.91 | PTK6 (0.46) | TTKPTK6LCKAURKB | |
| SCHEMBL22123962 | 0.91 | PTK6 (0.47) | TTKPTK6LCKAURKB | |
| SCHEMBL24870700 | 0.90 | PTK6 (0.50) | TTKPTK6LCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |