Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 11/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 8/20 | 0.36 |
| ▸ | JAK1 | P23458 | 7/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177742 | 1.00 | PTK6 (0.43) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22142969 | 0.96 | PTK6 (0.43) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL30172095 | 0.96 | PTK6 (0.43) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22124092 | 0.96 | PTK6 (0.43) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22139164 | 0.96 | PTK6 (0.43) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22124325 | 0.94 | PTK6 (0.46) | PTK6AURKBJAK2JAK1TTK | |
| Formic Acid SCHEMBL30171547 | 0.93 | PTK6 (0.42) | PTK6AURKBJAK2JAK1TTK | |
| Formic Acid SCHEMBL25175412 | 0.92 | PTK6 (0.44) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22139127 | 0.92 | PTK6 (0.48) | PTK6AURKBJAK2JAK1TTK | |
| SCHEMBL22123779 | 0.91 | PTK6 (0.52) | PTK6AURKBTTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | claimed |
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |