Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.37 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178037 | 1.00 | PTK6 (0.44) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL22124561 | 0.95 | PTK6 (0.44) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL22142981 | 0.95 | PTK6 (0.44) | PTK6AURKBLCKCCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL30171884 | 0.94 | PTK6 (0.44) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL22124089 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL30177866 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL30171923 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL22125166 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL22124393 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 | |
| SCHEMBL30171641 | 0.94 | PTK6 (0.43) | PTK6AURKBLCKCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | claimed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | claimed |
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |