Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 18/20 | 0.49 |
| ▸ | LCK | P06239 | 7/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123956 | 0.97 | PTK6 (0.52) | PTK6LCKTTKAURKB | |
| SCHEMBL24911044 | 0.91 | PTK6 (0.53) | PTK6LCKTTKAURKB | |
| SCHEMBL22142832 | 0.90 | PTK6 (0.51) | PTK6LCKTTKAURKB | |
| SCHEMBL22123352 | 0.86 | PTK6 (0.47) | PTK6LCKTTKAURKB | |
| Formic Acid SCHEMBL30171586 | 0.84 | PTK6 (0.44) | PTK6LCKTTKAURKB | |
| SCHEMBL22123974 | 0.84 | PTK6 (0.48) | PTK6LCKTTKAURKB | |
| Formic Acid SCHEMBL30171728 | 0.84 | PTK6 (0.42) | PTK6LCKTTKAURKB | |
| Hydrochloric Acid SCHEMBL30172070 | 0.83 | PTK6 (0.47) | PTK6LCKTTKAURKB | |
| Formic Acid SCHEMBL30171853 | 0.83 | MAPKAPK5 (0.45) | PTK6LCKTTKAURKB | |
| SCHEMBL22123966 | 0.83 | PTK6 (0.49) | PTK6LCKTTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| EP-3897840-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| EP-3898629-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| EP-3898630-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |