Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502943 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2HRH3 | |
| SCHEMBL954379 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL26678224 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2HRH3 | |
| SCHEMBL986211 | 0.79 | SLC18A3 (0.38) | OPRM1OPRD1OPRK1OGFRL1OPRL1 | |
| SCHEMBL1306715 | 0.79 | SLC18A3 (0.42) | OPRM1OPRD1OPRK1OGFRL1OPRL1 | |
| SCHEMBL10140528 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HRH3MAPTCYP2D6KCNH2 | |
| SCHEMBL222504 | 0.78 | KDM1A (0.34) | OPRM1OPRD1OPRK1OGFRL1CYP2D6 | |
| SCHEMBL30832687 | 0.77 | DPP4 (0.39) | SMN1; SMN2 | |
| SCHEMBL3958871 | 0.77 | SLC18A3 (0.45) | OPRM1OPRD1OPRK1OGFRL1OPRL1 | |
| SCHEMBL550979 | 0.77 | SLC18A3 (0.45) | OPRM1OPRD1OPRK1OGFRL1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113195496-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |