⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394066 | 0.75 | — | — | |
| SCHEMBL23234265 | 0.55 | MEN1 (0.41) | — | |
| SCHEMBL2056746 | 0.55 | — | — | |
| SCHEMBL9673094 | 0.55 | — | — | |
| SCHEMBL1261339 | 0.55 | — | — | |
| SCHEMBL9202192 | 0.55 | — | — | |
| SCHEMBL3464133 | 0.55 | — | — | |
| SCHEMBL10993767 | 0.53 | — | — | |
| SCHEMBL29663 | 0.52 | — | — | |
| SCHEMBL29664 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047267-A | Miscellaneous two ring [3.3.3] the hendecane compound of -5- bromines (hydrogen) of 1- azepine -5- germanium and its synthetic method | 中国科学技术大学 | 2018-05-18 | — | — | CN | disclosed |
| US-7982032-B2 | reacting Dibenzo[b,f]azepine-5-carbonylchloride with alkali metal methoxide to yield 10-Methoxy-dibenz[b,f]azepine | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2011-07-19 | — | — | US | disclosed |
| US-20080269480-A1 | Process for the Preparation of 10,11-Dihydro-10-Oxo-5H-Dibenz[B,F] Azepine-5-Carboxamide | MUTHUKUMARAN MANDAKINI | 2008-10-30 | — | — | US | disclosed |
| WO-2005096709-A2 | A PROCESS FOR THE PREPARATION OF 10,11-DIHYDRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2005-10-20 | — | — | WO | disclosed |