Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 10/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | TTK | P33981 | 4/20 | 0.38 |
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124496 | 1.00 | PTK6 (0.42) | PTK6AURKBTTKSYKMAPKAPK5 | |
| SCHEMBL22124096 | 1.00 | PTK6 (0.42) | PTK6AURKBTTKSYKMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL25174699 | 0.99 | PTK6 (0.41) | PTK6AURKBTTKSYKMAPKAPK5 | |
| SCHEMBL22124006 | 0.94 | PTK6 (0.43) | PTK6AURKBTTKSYKMAPKAPK5 | |
| SCHEMBL22124005 | 0.94 | PTK6 (0.43) | PTK6AURKBTTKSYKMAPKAPK5 | |
| SCHEMBL22124016 | 0.94 | PTK6 (0.43) | PTK6AURKBTTKSYKMAPKAPK5 | |
| Formic Acid SCHEMBL30171793 | 0.92 | PTK6 (0.42) | PTK6AURKBTTKSYKLCK | |
| Formic Acid SCHEMBL30171717 | 0.92 | PTK6 (0.42) | PTK6AURKBTTKSYKLCK | |
| SCHEMBL22124078 | 0.91 | PTK6 (0.43) | PTK6AURKBTTKSYKMAPKAPK5 | |
| SCHEMBL22139116 | 0.90 | PTK6 (0.41) | PTK6AURKBTTKSYKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | claimed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | claimed |