Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 13/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.44 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177743 | 1.00 | PTK6 (0.47) | PTK6AURKBMAPKAPK5TTKBRD4 | |
| SCHEMBL22124469 | 1.00 | PTK6 (0.47) | PTK6AURKBMAPKAPK5TTKBRD4 | |
| SCHEMBL22139235 | 0.89 | PTK6 (0.51) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL30172074 | 0.88 | PTK6 (0.47) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22125056 | 0.88 | PTK6 (0.47) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22123896 | 0.88 | PTK6 (0.61) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22124033 | 0.88 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22124365 | 0.87 | PTK6 (0.46) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL30177874 | 0.87 | PTK6 (0.46) | PTK6AURKBMAPKAPK5TTKLCK | |
| Hydrochloric Acid SCHEMBL30171630 | 0.87 | PTK6 (0.60) | PTK6AURKBMAPKAPK5TTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |