Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.51 |
| ▸ | CCR1 | P32246 | 5/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6103660 | 0.99 | CCR3 (0.50) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL12511626 | 0.93 | CCR3 (0.51) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL2211170 | 0.92 | CCR3 (0.60) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL2213688 | 0.92 | CCR3 (0.48) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL2215172 | 0.91 | CCR3 (0.60) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL2214048 | 0.90 | CCR3 (0.55) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL2215910 | 0.90 | CCR3 (0.48) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL2214242 | 0.88 | CCR3 (0.52) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL2211959 | 0.84 | CCR3 (0.59) | CCR3CCR1SIGMAR1MCHR1MEN1 | |
| SCHEMBL2213572 | 0.83 | CCR3 (0.57) | CCR3CCR1SIGMAR1MCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |