⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22128369 | 0.91 | — | — | |
| SCHEMBL22128414 | 0.91 | — | — | |
| SCHEMBL22128175 | 0.91 | — | — | |
| SCHEMBL22122390 | 0.87 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL22122260 | 0.87 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL22128381 | 0.87 | — | — | |
| SCHEMBL22128251 | 0.85 | — | — | |
| SCHEMBL22122373 | 0.84 | — | — | |
| SCHEMBL22122269 | 0.83 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL22122325 | 0.83 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139185-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2024-05-02 | — | — | US | disclosed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | disclosed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | disclosed |