Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874944 | 0.79 | BCHE (0.59) | BCHEACHECES1CYP3A4TDP1 | |
| SCHEMBL19358248 | 0.76 | CYP3A4 (0.46) | BCHEACHECES1CYP3A4TDP1 | |
| SCHEMBL2699746 | 0.75 | BCHE (1.00) | BCHEACHECES1CYP3A4TDP1 | |
| SCHEMBL767178 | 0.75 | MEN1 (0.63) | CYP3A4TDP1PARP1NPSR1MEN1 | |
| SCHEMBL9290363 | 0.73 | BCHE (0.51) | BCHEACHECES1CYP3A4TDP1 | |
| SCHEMBL28414966 | 0.73 | CYP1B1 (0.55) | BCHEACHECES1TDP1NPSR1 | |
| SCHEMBL421305 | 0.73 | CYP3A4 (0.50) | CYP3A4TDP1S100A4TRPV1XDH | |
| SCHEMBL29716114 | 0.72 | PARP1 (0.59) | CYP3A4TDP1MAOAMAOBPARP1 | |
| SCHEMBL278438 | 0.72 | PARP1 (0.59) | CYP3A4TDP1MAOAMAOBPARP1 | |
| SCHEMBL9503458 | 0.70 | CYP3A4 (0.51) | BCHEACHECES1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333623-A | Fluorescent dye for lysosome marking and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-111337460-A | High-stability Halo-tag probe and synthesis and biological application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-111334072-A | Mitochondrial super-resolution fluorescent dye with high brightness and high stability | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-111334084-A | Mitochondrial fluorescent dye with high brightness, high stability and high permeability | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-111333619-B | 488nm excited high-stability super-resolution fluorescent dye and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-111333576-B | High-stability wash-free Halo-tag probe and synthetic method and biological application thereof | 中国科学院大连化学物理研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-111333622-B | High-brightness and high-stability fluorescent dye containing active ester and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-111333640-B | Fluorescent probe for rapidly and specifically labeling SNAP-tag as well as preparation and biological application thereof | 中国科学院大连化学物理研究所 | 2022-06-03 | — | — | CN | disclosed |
| CN-111333641-B | Enhanced fluorescent probe for tetrazine bio-orthogonal labeling and synthesis thereof | 中国科学院大连化学物理研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-111334077-B | 488nm excited high-brightness and high-stability fluorescent dye and synthetic method thereof | 中国科学院大连化学物理研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-111333624-B | High-stability wash-free SNAP-tag probe and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-03-18 | — | — | CN | disclosed |
| CN-111333618-B | 488nm excited wash-free SNAP-tag probe and preparation method thereof | 中国科学院大连化学物理研究所 | 2022-03-18 | — | — | CN | disclosed |
| CN-111333623-A | Fluorescent dye for lysosome marking and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111334083-A | High-brightness high-stability active fluorescent dye and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333646-A | High-brightness high-stability wash-free SNAP-tag probe and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111337460-A | High-stability Halo-tag probe and synthesis and biological application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333622-A | High-brightness and high-stability fluorescent dye containing active ester and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333624-A | High-stability wash-free SNAP-tag probe and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333677-A | 488nm excited mitochondria fluorescent probe and preparation and biological application thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | disclosed |
| WO-2020124688-A1 | FULL-SPECTRUM HIGH-BRIGHTNESS AND HIGH-STABILITY FLUORESCENT DYES, AND SYNTHESIS AND APPLICATION THEREOF | 中国科学院大连化学物理研究所 | 2020-06-25 | — | — | WO | disclosed |