SCHEMBL22129682

SCHEMBL22129682

[CH2]C(CCCCCCCCCC)CCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 1/20 0.48
DNM1 Q05193 2/20 0.48
OPRM1 P35372 1/20 0.46
GPR84 Q9NQS5 3/20 0.42
FDPS P14324 3/20 0.42
SPHK1 Q9NYA1 1/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200824 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL8430564 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL198605 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL6658137 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL2584365 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22129787 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22407241 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22407234 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22129681 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL199154 1.00 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020129944-A1 LUBRICATING BASE OIL FOR FLUID DYNAMIC BEARING 新日本理化株式会社 2020-06-25 WO disclosed
CN-103570714-B A kind of synthon and utilize synthon to prepare the method for the cool compounds of dibenzo BEIJING PRINT COLLEGE (CN) 2016-05-11 CN disclosed
CN-103509019-B Cool compounds of a kind of dibenzo and preparation method thereof BEIJING PRINT COLLEGE (CN) 2015-11-04 CN disclosed
CN-103570714-A Synthon and method for preparing dibenzocoronene compounds by same BEIJING INST GRAPHIC COMM 2014-02-12 CN disclosed
CN-103509019-A Dibenzocoronene compound and preparation method thereof BEIJING INST GRAPHIC COMM 2014-01-15 CN disclosed