Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.70 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360651 | 0.82 | DYRK1A (0.74) | DYRK1AGRM5KDM4EALDH1A1HPGD | |
| SCHEMBL22130319 | 0.79 | DYRK1A (0.70) | DYRK1AUSP30GRM5KDM4EALDH1A1 | |
| SCHEMBL12403385 | 0.76 | DYRK1A (0.64) | DYRK1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL30639453 | 0.75 | DYRK1A (0.63) | DYRK1AUSP30GRM5RETCLK4 | |
| SCHEMBL1829687 | 0.72 | DYRK1A (0.59) | DYRK1AUSP30GRM5 | |
| SCHEMBL30639477 | 0.72 | DYRK1A (0.64) | DYRK1AUSP30GRM5MAPT | |
| SCHEMBL21436086 | 0.72 | DYRK1A (0.59) | DYRK1AGRM5KDM4EALDH1A1GLA | |
| SCHEMBL20208549 | 0.72 | DYRK1A (0.59) | DYRK1AGRM5KDM4EALDH1A1NAMPT | |
| SCHEMBL24706350 | 0.70 | DYRK1A (0.51) | DYRK1AUSP30GRM5KDM4EALDH1A1 | |
| Cyanide SCHEMBL22130120 | 0.69 | DYRK1A (0.55) | DYRK1AUSP30RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020130214-A1 | NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF | 한국과학기술연구원 | 2020-06-25 | — | — | WO | disclosed |