Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELAVL1 | Q15717 | 5/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22130646 | 0.89 | ELAVL1 (0.56) | ELAVL1MTNR1AMTNR1BPDCD1CD274 | |
| SCHEMBL22130648 | 0.82 | ELAVL1 (0.60) | ELAVL1ALOX5PTGS2 | |
| SCHEMBL22130680 | 0.78 | ELAVL1 (0.47) | ELAVL1TDP1 | |
| SCHEMBL22130729 | 0.78 | ELAVL1 (0.61) | ELAVL1ALOX5PTGS2 | |
| SCHEMBL22130713 | 0.77 | ELAVL1 (0.41) | ELAVL1MTNR1AMTNR1BPDCD1CD274 | |
| SCHEMBL22130717 | 0.73 | ELAVL1 (0.55) | ELAVL1MTNR1AMTNR1BKMT2ARORC | |
| SCHEMBL22130645 | 0.72 | ELAVL1 (0.62) | ELAVL1 | |
| SCHEMBL22130676 | 0.71 | KDM4E (0.40) | ELAVL1KDM4ERXFP1KMT2A | |
| SCHEMBL19737481 | 0.71 | ELAVL1 (1.00) | ELAVL1ALOX5PTGS2 | |
| SCHEMBL22130712 | 0.68 | ELAVL1 (0.55) | ELAVL1ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2020-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | AZI2, TPMT, TYMS | ELAVL1 2765/4885MTNR1A 1994/4885MTNR1B 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.