Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELAVL1 | Q15717 | 7/20 | 0.81 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737490 | 0.90 | ELAVL1 (1.00) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL22130694 | 0.89 | ELAVL1 (0.79) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL22130697 | 0.87 | ELAVL1 (0.79) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL21222486 | 0.86 | ELAVL1 (1.00) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL19737425 | 0.86 | ELAVL1 (0.83) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL22130634 | 0.86 | ELAVL1 (0.83) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL22130696 | 0.86 | ELAVL1 (0.74) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| Dimethylamine SCHEMBL21222569 | 0.85 | ELAVL1 (0.90) | ELAVL1HTR6L3MBTL1CA12CA1 | |
| SCHEMBL22130695 | 0.85 | ELAVL1 (0.76) | ELAVL1HTR6L3MBTL1CA12CA9 | |
| SCHEMBL22130632 | 0.83 | ELAVL1 (0.77) | ELAVL1HTR6L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2020-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | AZI2, TPMT, TYMS | ELAVL1 2765/4885HTR6 1922/4885L3MBTL1 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.