Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.56 |
| ▸ | CCR1 | P32246 | 5/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213254 | 1.00 | CCR3 (0.56) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2212053 | 0.93 | CCR3 (0.55) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2213144 | 0.93 | CCR3 (0.56) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2215033 | 0.93 | CCR3 (0.56) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2211850 | 0.93 | CCR3 (0.54) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2213728 | 0.93 | CCR3 (0.57) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2210819 | 0.93 | CCR3 (0.57) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL12511802 | 0.92 | CCR3 (0.58) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2213896 | 0.92 | CCR3 (0.55) | CCR3CCR1SIGMAR1MEN1KMT2A | |
| SCHEMBL2213891 | 0.92 | CCR3 (0.55) | CCR3CCR1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |
| EP-1389616-A1 | NOVEL BENZYLPIPERIDINE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2004-02-18 | — | — | EP | disclosed |