SCHEMBL2213282

CCOC(=O)C(C)Oc1c(Cl)ccc(P(=O)(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)c2cc(C(C)(C)C)cc(C(C)(C)C)c2)c1-c1c(P(=O)(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)c2cc(C(C)(C)C)cc(C(C)(C)C)c2)ccc(Cl)c1O

nearest known ligand 0.32

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2213279	1.00	KMT2A (0.32)	KMT2A
SCHEMBL2206856	0.95	KMT2A (0.35)	KMT2A
SCHEMBL2206852	0.95	KMT2A (0.35)	KMT2A
SCHEMBL2212762	0.90	MEN1 (0.33)	KMT2A
SCHEMBL2212759	0.90	MEN1 (0.33)	KMT2A
SCHEMBL2210943	0.88	KMT2A (0.31)	KMT2A
SCHEMBL2210939	0.88	KMT2A (0.31)	KMT2A
SCHEMBL2210807	0.85	KMT2A (0.40)	KMT2A
SCHEMBL2210803	0.85	KMT2A (0.40)	KMT2A
SCHEMBL2212056	0.85	MAPT (0.35)	KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7981827-B2	Chiral phosphanes for use in asymmetric syntheses	BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE)	2011-07-19	—	—	US	disclosed