Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.55 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.55 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22186196 | 0.93 | FGFR1 (0.62) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132777 | 0.93 | FGFR1 (0.62) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22186197 | 0.93 | FGFR1 (0.62) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132920 | 0.83 | FGFR1 (0.64) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132833 | 0.83 | FGFR1 (0.64) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132822 | 0.83 | FGFR1 (0.64) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132836 | 0.82 | FGFR1 (0.61) | FGFR1FGFR3FGFR4 | |
| SCHEMBL27188671 | 0.81 | FGFR1 (0.53) | FGFR1FGFR3FGFR4 | |
| SCHEMBL27188670 | 0.81 | FGFR1 (0.53) | FGFR1FGFR3FGFR4 | |
| SCHEMBL22132847 | 0.78 | FGFR1 (0.53) | FGFR1FGFR3FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670513-B1 | FGFR INHIBITOR AND MEDICAL APPLICATION THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2023-09-20 | — | — | EP | disclosed |
| EP-3670513-A1 | FGFR INHIBITOR AND MEDICAL APPLICATION THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2020-06-24 | — | — | EP | disclosed |