Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121416 | 0.83 | KMT2A (0.57) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19437489 | 0.82 | POLB (0.60) | ACSS2KMT2ACYP1A2CYP2D6HTT | |
| SCHEMBL19451751 | 0.78 | KMT2A (0.42) | KMT2ACYP1A2CYP2D6HTTTLR8 | |
| SCHEMBL22151665 | 0.77 | KDM4E (0.55) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL22121494 | 0.77 | KDM4E (0.50) | ACSS2KMT2AHTTCHEK2F2R | |
| SCHEMBL22121411 | 0.75 | KMT2A (0.52) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19436528 | 0.74 | KMT2A (0.50) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19436567 | 0.74 | KMT2A (0.50) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL20066406 | 0.74 | KMT2A (0.47) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19437503 | 0.73 | KMT2A (0.74) | KMT2ACYP1A2CYP2D6HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |