SCHEMBL22135083

SCHEMBL22135083

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1CCCNC(=O)N(C)Cc1ccncc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135181 0.94 STING1 (0.80) STING1
SCHEMBL22135258 0.93 STING1 (0.79) STING1
SCHEMBL22135301 0.91 STING1 (0.79) STING1
SCHEMBL22135186 0.90 STING1 (0.70) STING1
SCHEMBL28392585 0.89 STING1 (0.82) STING1
SCHEMBL22135076 0.89 STING1 (1.00) STING1
SCHEMBL22135007 0.89 STING1 (0.70) STING1
SCHEMBL22135178 0.89 STING1 (0.76) STING1
SCHEMBL22135198 0.89 STING1 (0.72) STING1
SCHEMBL22135032 0.88 STING1 (0.76) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed