Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.64 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22134990 | 0.96 | STING1 (0.65) | STING1TBK1 | |
| SCHEMBL22135094 | 0.93 | STING1 (0.66) | STING1TBK1 | |
| SCHEMBL22135322 | 0.91 | STING1 (0.69) | STING1TBK1 | |
| SCHEMBL22150054 | 0.88 | STING1 (0.65) | STING1TBK1 | |
| SCHEMBL22151352 | 0.86 | STING1 (0.77) | STING1TBK1 | |
| SCHEMBL22121262 | 0.84 | STING1 (0.50) | STING1TBK1 | |
| SCHEMBL22150053 | 0.83 | STING1 (0.58) | STING1TBK1 | |
| SCHEMBL22135087 | 0.82 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL22151323 | 0.81 | STING1 (0.68) | STING1TBK1 | |
| SCHEMBL22150552 | 0.81 | STING1 (0.69) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |