SCHEMBL22135354

SCHEMBL22135354

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1CCCNC(=O)OCc1ccccc1OCC1CC1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135209 0.89 STING1 (0.90) STING1
SCHEMBL19449091 0.87 STING1 (1.00) STING1
SCHEMBL22135075 0.86 STING1 (0.84) STING1
SCHEMBL22135098 0.85 STING1 (0.79) STING1
SCHEMBL22135003 0.85 STING1 (0.77) STING1
SCHEMBL22135211 0.85 STING1 (1.00) STING1
SCHEMBL22135324 0.84 STING1 (0.82) STING1
SCHEMBL22135216 0.84 STING1 (0.91) STING1
SCHEMBL22135221 0.84 STING1 (0.79) STING1
SCHEMBL22135076 0.83 STING1 (1.00) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 — — WO disclosed
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