Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.75 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135356 | 0.90 | STING1 (0.68) | STING1TBK1HTTMAP3K7KDM4E | |
| SCHEMBL19437599 | 0.85 | STING1 (1.00) | STING1TBK1MAP3K7 | |
| SCHEMBL21648071 | 0.85 | STING1 (0.82) | STING1TBK1MAP3K7KMT2A | |
| SCHEMBL23346495 | 0.85 | STING1 (0.82) | STING1TBK1 | |
| SCHEMBL22135257 | 0.82 | STING1 (0.91) | STING1TBK1HTTMAP3K7KDM4E | |
| SCHEMBL19437563 | 0.82 | STING1 (0.75) | STING1 | |
| SCHEMBL22135964 | 0.81 | STING1 (0.62) | STING1TBK1HTTMAP3K7KDM4E | |
| SCHEMBL19451762 | 0.81 | STING1 (0.93) | STING1TBK1 | |
| SCHEMBL29702073 | 0.81 | STING1 (0.93) | STING1TBK1 | |
| SCHEMBL22118178 | 0.81 | STING1 (0.66) | STING1TBK1HTTMAP3K7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |