Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135751 | 1.00 | CYP2D6 (0.55) | CYP2D6KCNH2CHRM4DRD2HTR7 | |
| SCHEMBL22135732 | 0.89 | CYP2D6 (0.55) | CYP2D6KCNH2ALDH1A1GAACASP6 | |
| SCHEMBL22135730 | 0.89 | CYP2D6 (0.55) | CYP2D6KCNH2ALDH1A1GAACASP6 | |
| SCHEMBL22135757 | 0.87 | CYP2D6 (0.58) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL4191954 | 0.86 | CYP2D6 (0.70) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL30455081 | 0.86 | CYP2D6 (0.70) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL22135733 | 0.86 | CYP2D6 (0.70) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL22118714 | 0.85 | CYP2D6 (0.52) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL22135801 | 0.85 | CYP2D6 (0.52) | CYP2D6KCNH2GAACASP6DHODH | |
| SCHEMBL29478217 | 0.85 | CYP2D6 (0.52) | CYP2D6KCNH2GAACASP6DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131573-A1 | COMPOUNDS FOR THE REDUCTION OF THE DELETERIOUS ACTIVITY OF EXTENDED NUCLEOTIDE REPEAT CONTAINING GENES | NUREDIS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |