Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DNM2 | P50570 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222582 | 1.00 | ABL1 (0.51) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL27342096 | 1.00 | ABL1 (0.51) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL28754761 | 1.00 | ABL1 (0.51) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL27619421 | 1.00 | ABL1 (0.51) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL8744011 | 1.00 | ABL1 (0.51) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL2059186 | 0.98 | ABL1 (0.49) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL7360731 | 0.92 | MAPT (0.43) | ABL1KCNH3PRSS1MAPTALDH1A1 | |
| SCHEMBL9506930 | 0.89 | ABL1 (0.59) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL3395174 | 0.89 | ABL1 (0.59) | ABL1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL16439908 | 0.89 | ABL1 (0.59) | ABL1KCNH3PRSS1F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | claimed |
| CN-1933827-A | Use of methylene amide derivatives in cardiovascular disorders | APPLIED RESEARCH SYSTEMS (AN) | 2007-03-21 | — | — | CN | claimed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | claimed |
| US-20220404729-A1 | TONER PARTICLES FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE AND TONER COMPOSITION FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE | TOMOEGAWA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-114450642-A | Toner particles for developing electrostatic charge image and toner composition for developing electrostatic charge image | 株式会社巴川制纸所 | 2022-05-06 | — | — | CN | disclosed |
| EP-2690498-B1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-8999620-B2 | Toner for electrostatic latent image development | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8980515-B2 | Magnetic toner for electrostatic latent image development | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140045114-A1 | MAGNETIC TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140038097-A1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140030647-A1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-6686112-B2 | MIXTURE OF COLORED PARTICLES, RELEASE AGENTS AND POLYMER RESIN; OFFSET RESISTANCE | SEIKO EPSON CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20020160289-A1 | Electrophotographing dry-type toner and production method therefor | SEIKO EPSON CORPORATION (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1178360-A1 | ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR | SEIKO EPSON CORPORATION (JP) | 2002-02-06 | — | — | EP | disclosed |
| US-5618980-A | DEHYDROGENATING N-CYCLOHEXYLIDENEAMINO COMPOUND IN PRESENCE OF HYDROGEN TRANSFER CATALYST AND HYDROGEN ACCEPTOR AND ALKALI OR ALKALINE EARTH METAL COMPOUND COCATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-04-08 | — | — | US | disclosed |
| EP-0588060-B1 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0753505-A2 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5536878-A | HYDROGEN ACCEPTOR | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5382690-A | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0588060-A2 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-03-23 | — | — | EP | disclosed |