Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.73 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.73 |
| ▸ | STAT3 | P40763 | 2/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379831 | 0.97 | CRBN (0.71) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL25917709 | 0.97 | CRBN (0.70) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL23015901 | 0.97 | CRBN (0.70) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL19764193 | 0.97 | CRBN (0.70) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL21163040 | 0.95 | CRBN (0.75) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL26320196 | 0.95 | STAT3 (0.76) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL19764198 | 0.94 | CRBN (0.67) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL23584020 | 0.94 | CRBN (0.71) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL18494154 | 0.93 | CRBN (0.67) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL24391010 | 0.92 | CRBN (0.74) | CRBNDDB1STAT3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |